The Gods, anthropomorphism, and the No-God. So far the acting Gods in the series are exclusively human Gods. There are no Nonmen Gods that take action, no Inchoroi Gods, only human Gods. Let's consider this from the Outside perspective. The Gods are Eternal and everywhere, having no ontological limits, only intentional distinctions defining their nature. This means that any other, non-human Gods, should likewise be eternal and omnipresent. Yet there is no evidence of them. This leads me to think that the universe of the Second Apocalypse is entirely anthropomorphic. Only human existence is connected to the Gods, and they define each other through a kind of loop (the Gods exist forever and influence humans, humans worship the Gods that influenced them, giving rise to said Gods, then the Gods influence humans, and so on).
This is a bit hard to grasp. Humans have ontological perspective of things, while the Gods have Eternal perspective. Being created somewhere in the timeline, the Gods then exist for the whole of that timeline, ensuring their own creation. The Gods act without time restrictions, so every action they take was always taken, is always taken, and will be always taken. When the universe somehow changes without the knowledge of the Gods (say, by the No-God), the Gods instantly populate new timeline differently. It accounts for any changes made, and also accounts for their previous actions (for example, Sorweel wasn't the White-Luck Warrior v. 2.0 while the first Warrior wasn't thwarted by Kelmomas, but the first Warrior was thwarted, so Sorweel was always meant to supplant him now that Yatwer is aware of the first Warrior's failure, and this turn of events already is incorporated in the timeline; at the same time, the first Warrior always existed, and so from Yatwer's perspective always should have existed, even if doomed to fail) The No-God, then, represents a different timeline, the one where there is no Gods. Their connection to the world and humans is severed, the loop of that connection is collapsed, and in the wake of this collapse another context arises, on which the Gods have no bearing whatsoever since in that context they do not exist nor have ever existed. If the Gods and their worshippers represent the dichotomy of consciousness and unconsciousness, then the No-God creates a context of "non-consciousness", which renders the aforementioned dichotomy meaningless. Among other things, this makes me think that the "blessed one hundred forty-four thousand" wouldn't just live normal (if horrifically tortured) lives; some kind of metaphysical transformation would be forced upon them.
This also explains the No-God's effect on the Gods. His non-consciousness is beyond the context of their existence, and so they can't do anything about it, can't even directly comprehend the possibility of the No-God's existence. It lacks any kind of connection to the Gods that would allow them to interact with it or even perceive it. When the No-God acts, the Gods are indeed witless, robbed of the ability to even comprehend the action taken. In this way, the No-God already is a seed of new metaphysical universe. Presumably, it needs more "parts" to fully "create" this new universe, and that's where the 144k come in. But the No-God can't use them if there are more people alive, since they are a part of the existing context, the "Gods context". So that context needs to be weakened.
That's roughly what I got for now.