If the Psuke is indeed significantly different, its not difficult to understand that it was a path that no one saw. If all you have is a hammer, all your problems look like nails, as they say.
Even still though, the timescales we are looking at really would seem to suggest that the nonmen should have had so development of the Psuke, unless there is some reason that they cannot wield it. A whole lot can happen with 10,000 years of metaphysical tinkering. Then again, the mighty detest change. A problem with overarching civilizations and stagnation.