Just finished the book, definitely worth the wait, my god. I'd say that this book has more concentrated awful than probably the whole first trilogy combined.
-Saubon being dragged to hell. Felt kind of bad for the guy even though he was obviously an asshole, especially since he'd just started believing.
-Normally you don't find too many likeable characters in this series, but Bakker introduced two in this book and killed em both off, in Koringhus and Oinaral. When Koringhus jumped, damn that got me. Oirinal being killed by his own father as well.
-The entire descent into the depths of Ishteribinth. I don't think anyone's ever devised a more awful fate for a fictional race. The whole idea that that is better than damnation makes it all the worse.
-Proyas being raped, of course. I always kind of root for the guy, very surprised he survived this book in all honesty.
-Thelli and Inrilatas.
-The descriptions following the nuke were pretty vivid. Really, most of the Great Ordeal in this book was horrific stuff to read. Made Mimira and Achamian's adventures seem like a fucking lighthearted subplot.
I'm sure there's so much more but I'm reeling a bit. Now to read all the existing discussion.