I've been listening to Dune over the last few weeks and I am hearing so many shades of TSA over the course of it. Most of the obvious things have been covered here, but interestingly enough, in one part, where Paul and Jessica are in the tent trying to figure out what to do now that Leto is dead, Paul refers to himself as a seed.
I haven't read all the other books yet, but I have an idea where it all goes, but I found that seemingly poignant (a la, Celmomas' words to Seswatha about Ishual).