Maybe it's something of the case that genetics and environment are both first and second-order effects?
In other words, neither is "the cause" even though it is somewhat trivially true that the genetics "comes before" the environment the genes will be in, really both the genes and environment are the "substrate of actualization?" One necessarily actualizing the other, by turns.
OK, well, I am not sure what I even wrote there. But it seems like something someone smart might say about this.