I picture it as a one off like Neuropath. A PKD style fast paced big ideas novel, heavy on action and cyberpunk trashy.
+1 - Semantica, for sure. Or a duology or something.
But SF deserves a full-on Bakker/TSA epic.
I want this so bad but I'm afraid he's just going to keep writing TSA material.
Which is itself not a bad thing (I feel like a prequel series after TNG is almost inevitable) but...a legit Bakker epic SF would be so. fucking. good.
I think given the choice between a new Bakker scifi series, or an immediate continuation of TSA through the end of TNG, I'd pick the former. Given what appears to be his present focus, based on his TPB posts and such, I think he's in a better headspace for a new scifi, and a break from TSA might make for better books in the future.